Peptide Category: Healing
Pegylated MGF
What is Pegylated MGF (PEG-MGF)? Pegylated MGF — commonly written as PEG-MGF — is a chemically modified form of Mechano Growth Factor (MGF), a splice variant of the insulin-like growth factor 1 (IGF-1) gene that the body produces locally in response to mechanical stress, particularly the microtrauma associated with intense muscle contraction. Understanding PEG-MGF requires
VIP
What is VIP (Vasoactive Intestinal Peptide)? Vasoactive Intestinal Peptide — almost universally shortened to VIP — is a 28-amino acid neuropeptide that belongs to the secretin/glucagon superfamily. First isolated in 1970 by Said and Mutt from porcine intestinal tissue, VIP was originally named for its potent vasodilatory activity. That early framing turned out to be
KPV
What is KPV? KPV is a tripeptide composed of three amino acids: lysine (K), proline (P), and valine (V). It represents the C-terminal fragment of alpha-melanocyte stimulating hormone (alpha-MSH), specifically the last three residues of that 13-amino acid peptide. This might seem like a minor structural footnote, but it turns out to be scientifically significant.
LL-37
What is LL-37? LL-37 is the only human member of the cathelicidin family of antimicrobial peptides — a distinction that immediately sets it apart from the hundreds of antimicrobial peptides identified in other species. Its name is both descriptive and specific: “LL” refers to the two leucine residues at its N-terminus, and “37” refers to
Pentosan Polysulfate
What is Pentosan Polysulfate (PPS)? Pentosan polysulfate sodium (PPS) occupies an unusual position in the research and clinical pharmacology landscape: it is both an FDA-approved prescription drug with decades of clinical use and, concurrently, an actively investigated compound for a growing list of conditions well beyond its original approved indication. Commercially marketed as Elmiron in
TB-500
What is TB-500? TB-500 is the common research designation for a synthetic fragment of thymosin beta-4 (Tβ4), one of the most ubiquitous and biologically active members of the beta-thymosin peptide family. The parent protein, thymosin beta-4, is a 43-amino acid peptide that was first isolated from calf thymus glands in the early 1970s by researchers
BPC-157
What is BPC-157? BPC-157 — Body Protection Compound 157 — is a synthetic pentadecapeptide consisting of 15 amino acids with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val. It is a partial sequence derived from a larger protective protein found in human gastric juice, where it was originally identified during the systematic fractionation of gastric secretions in the early 1990s.